Table 2 Concepts in the Mutation Impact Ontology and their descriptions.
From: Algorithms and semantic infrastructure for mutation impact extraction and grounding
Concept | Description |
|---|---|
Protein | Proteins, also known as polypeptides, are organic compounds made of amino acids arranged in a linear chain and folded into a globular form. |
Protein Mutant | A protein mutant is a protein where the amino acid sequence is altered compared to the wildtype protein. These alterations are called mutations. |
Protein Property | The physical, chemical and biological properties of proteins. Stability and Function to mention a couple. |
Elementary Mutation | An elementary change in the amino acid sequence of a protein. |
Mutation Series | A set of elementary mutations. |
Mutation Specification | An umbrella concept introduced as a link between mutations, their corresponding proteins, the impacts they cause and the texts. |
Mutation Impact | A mutation impact describes a directional alteration of a protein. |