Figure 3

Chromatin modifications, binding of transcription factors, and binding motifs in promoters of responsive and non-responsive genes. (A) DNA binding motifs over-represented in the promoters (<200 bp from TSS) of non-responsive and responsive genes with CpG islands; (B) Comparison of chromatin modifications [7, 18], binding of transcription factors [9, 16, 17], and binding motifs among responsive and non-responsive genes with CpG islands; "n/s" = non-significant, otherwise it is significant (p < 0.05); (C) Average strength of H3K4 tri-methylation measured by the number of ChIP-seq tags within 1 Kb from TSS of responsive and non-responsive genes, "n/s" = non-significant; (D) Average strength of H3K27 tri-methylation measured by the number of ChIP-seq tags within 3 Kb from TSS of responsive and non-responsive genes, "n/s" = non-significant. Numerical data for (C) and (D) is in Additional File 14.