Table 5 Common SOX2 targets of human GBM and ES cells that changed expression after SOX2 knockdown
Gene Symbol | Mock/SOX2 _KO ratios | Description |
|---|---|---|
ALCAM | 2.02 | activated leukocyte cell adhesion molecule |
BASP1 | 0.28 | brain abundant, membrane attached signal protein 1 |
BCAT1 | 0.38 | branched chain aminotransferase 1, cytosolic |
COL12A1 | 2.17 | collagen, type XII, alpha 1 |
CTH | 0.37 | cystathionase (cystathionine gamma-lyase) |
EBF3 | 2.03 | early B-cell factor 3 |
KLF5 | 0.49 | Kruppel-like factor 5 (intestinal) |
ONECUT1 | 0.48 | one cut domain, family member 1 |
PTHLH | 0.34 | parathyroid hormone-like hormone |
SLC30A1 | 0.38 | solute carrier family 30 (zinc transporter), member 1 |
SLC3A2 | 0.48 | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 |