Figure 3
Heatmap of differentially expressed probes in samples from S. epidermidis and S. aureus challenges. Hierarchical clustering was performed using Pearson-centred unsupervised statistics with GeneSpring®. Gene expression intensities are in rows (n = 261, FDR q-value < 0.05 and aFC > 5). Each column represents a sample. The level of gene expression is proportional to the colour scale. The genes in the top part of the graph are over-expressed in Se when compared to Sa samples, whereas it is the contrary for the bottom part of the graph. The cluster tree of the genes (left) illustrates the nodes of genes co-regulated in each Staphylococcus infection and their main functions are indicated. The cluster tree of samples above the heatmap graph enabled a perfect discrimination between S. aureus and S. epidermidis- challenged samples.