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Table 1 Metabolic parameters in aging mice

From: Characterization of age-related gene expression profiling in bone marrow and epididymal adipocytes

Parameter

 

6-month

14-month

 

Weight (g)

35.0 ± 1.2

41.8 ± 4.0*

 

Insulin (ng/mL)

0.57 ± 0.16

2.09 ± 0.44*

 

Glucose (mg/dL)

118.7 ± 12

192.7 ± 17*

 

Triglyceride (mg/dL)

240.9 ± 3.43

250.7 ± 6.8

Adipokines

   
 

Leptin (ng/mL)

3.52 ± 0.77

20.7 ± 2.38*

 

Resistin (ng/mL)

1.35 ± 0.17

1.85 ± 0.20

 

Adiponectin (μg/mL)

2.90 ± 0.20

5.66 ± 0.74*

Bone panel

  
 

Osteocalcin (ng/mL)

54.4 ± 4.8

31.8 ± 6.8*

 

RANKL (ng/mL)

0.21 ± 0.03

0.17 ± 0.22

 

Osteoprotegerin (ng/mL)

2.28 ± 0.40

1.92 ± 0.17

  1. Data are mean ± SE of 6 to 10 mice per age group. Body weights were determined at time of necropsy. Serum metabolites were measured in the fed state. * P < 0.05 vs. 6-month-old.
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BMC Genomics

ISSN: 1471-2164

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