Figure 4
Date Estimates of Key Events in Dehalococcoides Evolution. Maximum likelihood phylogeny of 432 'core' orthologs. Timing of key evolutionary events are mapped onto the tree. The horizontal line below the tree represents the divergence time to the Dehalococcoides (Dhc) and Dehalogenimonas (Dehly) MRCA, while vertical hash marks indicate the relative divergence times of Dehalococcoides ssrA genomic island (GI) components. These include Dehalococcoides ssrA integration modules, vcrABC-attached integration modules, and vcrAB. Relative divergence times are based on the estimated age of the MRCA of Dehalococcoides and Dehalogenimonas (set to 1). The scale bar represents 5% of the total divergence time. Absolute time scales are from published mutation rate estimates and rate estimates based on the Dehalococcoides strains DONNA2/strain 195 divergence. Black points on the tree are nodes with 100% bootstrap support.