Figure 1
From: Implication of next-generation sequencing on association studies
Allele frequency distribution for low coverage pilot and exon pilot autosomal SNPs. Figure 1 shows the MAF distribution from 0.5% to 5%. The red dashed line shows the MAF distribution expected for the standard neutral population model with constant population size and random mating, the blue solid line shows the MAF distribution for the all observed variants, and the green dotted line shows the MAF distribution for the observed non-synonymous alleles.