Multiple platform assessment of the EGF dependent transcriptome by microarray and deep tag sequencing analysis

BMC Genomics

Table 2 Functional analysis of differentially expressed EGF responsive genes.

TOP NETWORKS
Associated Network Functions	Focus Molecules	Score
1. Cell Death, Embryonic Development, Renal and Urological Disease	28	45
2. Amino Acid Metabolism, Post-Translational Modification, Small Molecule Biochemistry	26	40
3. Cell Cycle, Cancer, Cardiovascular System Development and Function	24	35
4. Cellular Growth and Proliferation, Hematological System and Connective Tissue Development and Function	24	35
5. Cellular Movement, Cellular Assembly and Organization, Cell-to-Cell Signaling and Interaction	24	35
TOP BIOLOGICAL FUNCTIONS
Molecular and Cellular Functions	p-value	Molecules
1. Cell Death	7.41e^-19-6.45e^-04	145
2. Cell Growth and Proliferation	1.77e^-16-6.15e^-04	160
3. Cellular Movement	3.16e^-12-6.50e^-04	101
4. Cellular Development	9.85e^-11-6.28e^-04	115
5. Cell Cycle	1.23e^-10-6.63e^-04	75
Diseases and Disorders	p-value	Molecules
1. Cancer	1.82e^-17-6.63e^-04	193
2. Reproductive System Disease	5.14e^-15-6.57e^-04	98
3. Immunological Disease	1.09e^-10-6.63e^-04	70
4. Dermatological Disease and Conditions	1.59e^-08-3.33e^-04	61
5. Inflammatory Disease	1.59e^-08-5.61e^-04	58

List of Ingenuity Networks and Biological Functions generated by mapping the 1164 focus molecules that were differentially expressed during EGF treatment according to RankProd.

ISSN: 1471-2164