Table 3 Dog genes and human orthologs within the selective sweep on CFA 26.
From: A selective sweep of >8 Mb on chromosome 26 in the Boxer genome
Boxer | |||||
|---|---|---|---|---|---|
Human gene | Dog gene | Start (bp) | End (bp) | Ensembl Gene ID | Annotation |
HIP1R | HIP1R | 9,641,249 | 9,654,192 | ENSCAFG00000007764 | Development of vertebral column |
P2RX4 | Q64F94_CANFA | 10,917,230 | 10,933,173 | ENSCAFG00000008363 | Contraction (and relaxation) of cardiac muscle |
P2RX7 | B0FLR1_CANFA | 10,959,759 | 11,002,514 | ENSCAFG00000008401 | Bone mineral density of skeleton Formation of perichondral bone Resorption of trabecular bone |
ATP2A2 | AT2A2_CANFA | 11,167,290 | 11,232,956 | ENSCAFG00000008434 | Contraction (and relaxation) of cardiac muscle Contraction and relaxation of papillary muscle Elongation of cardiomyocytes |
POLE | POLE | 3,436,073 | 3,481,729 | ENSCAFG00000006215 | Lymphoblastic lymphoma |
MYL2 | NP_001003069.1 | 11,482,695 | 11,650,673 | ENSCAFG00000008524 | Contraction of cardiac muscle Development of sarcomere Cardiomyopathy of heart ventricle |
Boxer, English and French bulldogs | |||||
Human gene | Dog gene | Start (bp) | End (bp) | Ensembl Gene ID | Annotation |
CCDC92 | CCDC92 | 8,759,998 | 8,790,267 | ENSCAFG00000006996 | Amino Acid Metabolism Protein Synthesis Small Molecule Biochemistry |
ATP6V0A2 | ATP6V0A2 | 8,929,687 | 8,968,952 | ENSCAFG00000007234 | Cutis laxa Wrinkly skin syndrome |
EIF2B1 | EIF2B1 | 9,029,462 | 9,038,275 | ENSCAFG00000007434 | Gene Expression Leukoencephalopathy with vanishing white matter Protein Synthesis |
DDX55 | DDX55 | 9,040,108 | 9,053,306 | ENSCAFG00000007452 | Cancer Infection Mechanism (by HIV) |
TMED2 | TMED2 | 9,056,220 | 9,064,265 | ENSCAFG00000007468 | Cancer Infection Mechanism (by HIV) |
SETD8 | 9,188,951 | 9,202,238 | ENSCAFG00000007493 | Tissue development and cell cycle |