Comparative analysis of methods for detecting interacting loci

BMC Genomics

Table 3 Properties of methods tested in this paper.

Name	Detection Principle	Heuristic search	Asymptotic null distribution	Free-accessible software
MDR	Prediction accuracy	Stochastic	No	http://www.multifactordimensionalityreduction.org/
FIM	Logistic regression	Deterministic	Yes	N/A
IG	Mutual Info.	N/A	No	N/A
BEAM	Bayesian model	Stochastic	Yes	http://www.fas.harvard.edu/~junliu/BEAM/
MECPM	BIC	Deterministic	No	http://www.cbil.ece.vt.edu/software/MECPM.zip
SH	χ²or B statistic	Deterministic	Yes	http://bioinformatics.ust.hk/SNPHarvester.html
LRIT	Logistic regression	N/A	Yes	N/A
LR	Logistic regression	N/A	Yes	N/A

For the methods without free-accessible software by the authors, we provide our self-written software, as well as C++ code, at http://code.google.com/p/simulation-tool-bmc-ms9169818735220977/downloads/list

ISSN: 1471-2164