Table 1 The DE genes associated with immune and inflammatory responses on PID 3
From: Transcription analysis on response of swine lung to H1N1 swine influenza virus
Functional classification | Gene description | Gene symbol | Fold Change | Gen Bank ID |
|---|---|---|---|---|
| Â | CD45 antigen isoform 3 Fragment | CD45 | 38.62459 | AK230523 |
| Â | Sus scrofa antibacterial protein | PMAP-23 | 21.70289 | EW419136 |
| Â | Sus scrofa peptide antibiotic PR39 | PR39 | 13.50724 | NM_214450 |
immune | Sus scrofa chemokine ligand 26-like mRNA | CCL26 | 8.645769 | NM_001078665 |
response | Sus scrofa protegrin 4 NPG4, mRNA | NPG4 | 8.237142 | NM_213863 |
| Â | Sus scrofa immunoglobulin kappa variable group | IGKV | 6.440473 | CB286369 |
| Â | Sus scrofa 2'-5'-oligoadenylate synthetase-like mRNA | OASL | 5.803129 | NM_001031790 |
| Â | Interferon-stimulated gene 20 kDa protein | ISG20 | 5.414398 | NM_001005351.2 |
| Â | Sus scrofa chemokine C-X-C motif ligand 10 mRNA | CXCL10 | 5.329808 | NM_001008691 |
| Â | Rep: IL-1 receptor 2-Bos taurus Bovine, partial 98% | IL1R2 | 5.321422 | NM_001046210.1 |
| Â | Sus scrofa MHC class II histocompatibility antigen | SLA-DQA1 | 5.232868 | AK230483 |
| Â | Sus scrofa cathepsin L1-like | CTSL1 | 4.814094 | AK230898 |
| Â | Sus scrofa interferon regulatory factor 3 (IRF3), mRNA | IRF3 | 4.320395 | NM_213770 |
| Â | Sus scrofa Fc fragment of IgG, low affinity IIb, receptor, mRNA | FCGR2B | 3.622257 | NM_001033013 |
| Â | Sus scrofa CD14 molecule, mRNA | CD14 | 3.544918 | NM_001097445 |
| Â | Sus scrofa interferon stimulated gene 15 mRNA | ISG15 | 3.45 | EU584557.1 |
| Â | Sus scrofa IgG heavy chain LOC396781, mRNA | IgG | 3.438582 | NM_213828 |
| Â | Sus scrofa interferon-induced protein with tetratricopeptide repeats 1 | IFI56 | 3.386147 | XM_001928724 |
| Â | Sus scrofa inducible T-cell co-stimulator ICOS, mRNA | ICOS | 3.353116 | NM_001044546 |
| Â | Sus scrofa interferon regulatory factor 7 IRF7, mRNA | IRF7 | 3.249327 | NM_001097428 |
| Â | Sus scrofa myxovirus influenza virus resistance 1, interferon-inducible protein p78 MX1, mRNA | MX1 | 3.237013 | NM_214061 |
| Â | Sus scrofa MHC class I antigen | SLA-2 | 3.187732 | AK231553 |
| Â | Sus scrofa cytotoxic T-lymphocyte-associated protein 4 CTLA4, mRNA | CTLA4 | 3.184663 | NM_214149 |
| Â | Sus scrofa DEAD Asp-Glu-Ala-Asp box polypeptide 58 DDX58, mRNA | DDX58 | 3.122048 | NM_213804 |
| Â | Rep:Tumor necrosis factor receptor superfamily member 17-Homo sapiens | TNFRSF17 | 3.071191 | NM_001192.2 |
| Â | Sus scrofa CD8a molecule CD8A, mRNA | CD8A | 2.834259 | NM_001001907 |
| Â | Similar to melanoma cell adhesion molecule | CD146 | -2.819245 | BX915975 |
| Â | similar to guanylate binding protein 4 | GBP4 | 2.780124 | AK239735 |
| Â | Sus scrofa guanylate binding protein 1, interferon-inducible, 67 kDa GBP1, mRNA | GBP1 | 2.765026 | NM_001128473 |
| Â | Sus scrofa ubiquitin specific peptidase 18, mRNA | USP18 | 2.732302 | NM_213826 |
| Â | Sus scrofa interferon-induced protein with tetratricopeptide repeats 2 mRNA | IFI54 | 2.729199 | AK230663 |
| Â | mast cell immunoreceptor signal transducer-like | CLNK | 2.704822 | AK237804 |
| Â | Rep:CD274 molecule CD274, mRNA- Homo sapiens | CD274 | 2.648947 | EW655654 |
| Â | Sus scrofa CD163 molecule CD163, mRNA | CD163 | 2.633336 | NM_213976 |
| Â | Sus scrofa interferon-induced protein 44 mRNA | IFI44 | 2.629777 | AK233687 |
| Â | Sus scrofa interleukin 12A natural killer cell stimulatory factor 1, IL12A, mRNA | IL12A | 2.580563 | NM_213993 |
| Â | Sus scrofa guanylate binding protein 2, interferon-inducible GBP2, mRNA | GBP2 | 2.561492 | NM_001128474 |
| Â | Sus scrofa interferon-induced protein with tetratricopeptide repeats 3, mRNA | IFI60 | 2.465327 | XM_001928703 |
| Â | Sus scrofa interferon-induced transmembrane protein 1 | IFITM1 | 2.407903 | AK237820 |
| Â | Sus scrofa chemokine C-C motif receptor 5, mRNA | CCR5 | 2.374719 | NM_001001618 |
| Â | Sus scrofa chemokine C-C motif receptor 10, mRNA | CCR10 | 2.36215 | NM_001044563 |
| Â | Sus scrofa chemokine C-C motif ligand 28, mRNA | CCL28 | 2.330211 | NM_001024695 |
| Â | Sus scrofa chemokine C-X-C motif ligand 9 mRNA | CXCL9 | 2.312722 | BP169836 |
| Â | Sus scrofa transporter 1, ATP-binding cassette, sub-family B MDR/TAP TAP1, mRNA | TAP1 | 2.15635 | NM_001044581 |
| Â | Sus scrofa Fas ligand TNF superfamily, member 6, mRNA | FAS | 2.098484 | NM_213806 |
| Â | Sus scrofa immunoglobulin-associated alpha CD79A, mRNA | CD79A | 2.086904 | NM_001135962 |
| Â | Sus scrofa interferon induced with helicase C domain 1 IFIH1, mRNA | IFIH1 | 2.075703 | NM_001100194 |
| Â | Sus scrofa aquaporin 9, mRNA | AQP9 | 2.067154 | NM_001112684 |
| Â | Sus scrofa tumor necrosis factor superfamily member 18 mRNA, partial cds | TNFSF18 | 2.065184 | DQ995649 |
| Â | Sus scrofa 2'-5'-oligoadenylate synthetase 2, 69/71kDa OAS2, mRNA | OAS2 | 2.054377 | NM_001031796 |
| Â | similar to cystatin F | CST7 | 2.042642 | CJ009409 |
| Â | Sus scrofa Ig gamma 2b chain constant region | IGG2B | 2.017483 | AK237225 |
| Â | Sus scrofa CD86 molecule CD86, mRNA | CD86 | 2.007655 | NM_214222 |
| Â | Sus scrofa vitronectin VTN, mRNA | VTN | -2.006228 | NM_214104 |
| Â | Sus scrofa chemokine ligand 26-like protein LOC780409, mRNA | CCL26 | 8.645769 | NM_001078665 |
| Â | Sus scrofa Toll-like receptor 3 | TLR3 | 7.331916 | NM_001097444.1 |
| Â | Sus scrofa chemokine C-X-C motif ligand 10, mRNA | CXCL10 | 5.329808 | NM_001008691 |
| Â | Sus scrofa selectin L (SELL), mRNA | SELL | 4.497706 | NM_001112678 |
inflammatory | Sus scrofa inflammatory response protein 6, mRNA | IRG6 | 3.840661 | NM_213817 |
response | Sus scrofa C1q-related factor LOC780424, mRNA | CRF | 3.627351 | NM_001078676 |
| Â | Sus scrofa CD14 molecule CD14, mRNA | CD14 | 3.544918 | NM_001097445 |
| Â | Sus scrofa alpha-1-antichymotrypsin 2 SERPINA3-2 | SERPINA3 | 3.119463 | NM_213787 |
| Â | Sus scrofa complement C4 C4, mRNA | C4 | 2.949702 | NM_001123089 |
| Â | Sus scrofa selectin E SELE, mRNA | SELE | -2.879741 | NM_214268 |
| Â | Sus scrofa toll-like receptor 2 (TLR2), mRNA | TLR2 | 2.8723 | NM_213761 |
| Â | Similar to melanoma cell adhesion molecule | CD146 | -2.819245 | BX915975 |
| Â | Sus scrofa toll-like receptor 8 TLR8, mRNA | TLR8 | 2.675719 | NM_214187 |
| Â | Sus scrofa CD163 molecule CD163, mRNA | CD163 | 2.633336 | NM_213976 |
| Â | Rep: transforming growth factor, beta 2- Macaca mulatta | TGFB2 | -2.554227 | EV858461 |
| Â | Sus scrofa chemokine C-C motif receptor 5, mRNA | CCR5 | 2.374719 | NM_001001618 |
| Â | Sus scrofa chemokine C-C motif ligand 28, mRNA | CCL28 | 2.330211 | NM_001024695 |
| Â | Sus scrofa chemokine C-X-C motif ligand 9 | CXCL9 | 2.312722 | BP169836 |
| Â | Sus scrofa serpin peptidase inhibitor, clade E member 1 SERPINE1, mRNA | SERPINE1 | 2.225002 | NM_213910 |
| Â | Sus scrofa Toll-like receptor 9 TLR9, mRNA | TLR9 | 2.200666 | NM_213958 |
| Â | Rep: arachidonate 15-lipoxygenase Alox15 gene- Mus musculus | Alox15 | -2.168114 | AK238353 |
| Â | Sus scrofa signal transducer and activator of transcription 1 STAT1, mRNA | STAT1 | 2.116864 | NM_213769 |
| Â | Sus scrofa S100 calcium binding protein A2 | S100A2 | 2.04835 | XM_001929556 |
| Â | Sus scrofa serpin peptidase inhibitor, clade G1 inhibitor, member 1 SERPING1, mRNA | SERPING1 | 2.022489 | NM_001123194 |