Figure 4

Raw intensity scatter plots. Raw intensities for all probes (n = 24526) were compared for (A) whole blood RNA and globin reduced RNA with IVT, (B) whole blood RNA with DAP+ and whole blood RNA with DAP-, (C) whole blood RNA and globin reduced RNA with DAP+, and (D) whole blood RNA with DAP- and globin reduced RNA with DAP-. Correlations for sample 1 are depicted. Average correlations for paired WB IVT versus GR IVT, WB DAP+ versus WB DAP-, WB DAP+ versus GR DAP+, and WB DAP- versus GR DAP- samples are 0.955, 0.992, 0.976, and 0.979, respectively. All 8 hemoglobin genes assayed on Illumina BeadChip Human-Ref v3.0 are labelled: HBA2, HBB, HBD, HBE1, HBG1, HBG2, HBM, HBQ, and HBZ. GLOBINclear specifically targets only HBA2 and HBB for reduction.