Figure 1

Schematic circular diagrams of the S. suis SS12 (A), D9 (B), D12 (C) and ST1 genomes (D). Key for circular diagrams (outside to inside): scale (in kb); annotated CDSs are shown on a pair of concentric circles representing both coding strands (positive in red, negative in blue); COG functional classification, CDSs colored according to predicted functions; tRNAs and rRNAs, 16S rRNA displayed in red, 23S rRNA in blue, 5S rRNA in yellow, tRNA on positive strand in black, tRNA on negative strand in green; GC skew plot (>0% yellow, <0% green); G+C% content plot. Color coding for CDS functions: dark blue, pathogenicity/adaptation; black, energy metabolism; red, information transfer; dark green, surface-associated; cyan, degradation of large molecules; magenta, degradation of small molecules; yellow, central/intermediary metabolism; pale green, unknown; pale blue, regulators; orange, conserved hypothetical; brown, pseudogenes; pink, phage and IS elements; gray, miscellaneous.