Table 3 Population-specific test on the long-term evolutionary status for the SNPs from the 890 associations from the Global Set.
From: Recent human evolution has shaped geographical differences in susceptibility to disease
Europeans (CEU)a | East Asians (CHB)a | East Asians (JPT)a | Africans (YRI)a | |||||
|---|---|---|---|---|---|---|---|---|
Replicability | ANCb(%) | DERb(%) | ANCb(%) | DERb(%) | ANCb(%) | DERb(%) | ANCb(%) | DERb(%) |
≤66.67% | 19017 | 4533 | 18529 | 4991 | 18623 | 4919 | 19816 | 3757 |
(n = 441) | (80.8) | (19.2) | (78.8) | (21.2) | (79.1) | (20.9) | (84.1) | (15.9) |
≥66.67% | 19783 | 5173 | 19271 | 5620 | 19334 | 5556 | 20789 | 4187 |
(n = 441) | (79.3) | (20.7) | (77.4) | (22.6) | (77.7) | (22.3) | (83.2) | (16.8) |
p-value | 4.89 × 10 -5 | p-value | 3.19 × 10 -4 | p-value | 1.43 × 10 -4 | p-value | 0.0144 | |