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Figure 3 | BMC Genomics

Figure 3

From: The association of DNA damage response and nucleotide level modulation with the antibacterial mechanism of the anti-folate drug Trimethoprim

Figure 3

SOS response is uniquely associated with thymineless induced lethality across treatment regimens and growth conditions. Heatmap of gene set scores associated with TMP treatment and thymineless death (TLD)[37]. Blue and yellow color refers to down-regulation and up-regulation of gene sets respectively. Condition labels are as described in Table 1. dRP: deoxyribosephosphate; SS: supercoiling; PBP: periplasmic binding proteins.

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BMC Genomics

ISSN: 1471-2164

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