Figure 9From: The repertoire of G protein-coupled receptors in the human parasite Schistosoma mansoni and the model organism Schmidtea mediterraneaSchematic of glutamate in association with LBD residues. Conserved mGluR LBD residues involved in glutamate binding are shown (underlined) in comparison with the corresponding residues for flatworm Glutamate-like receptors GSMP128940 and GSMD004608. Numbers represent residue location with respect to the mouse mGluR3 sequence. Disagreement at a given position is highlighted in red. GSMP128940 displays overall divergence with the canonical glutamate binding pocket, while GSMD004608 retains only key residues that interact with the glutamate α-carboxylic and α-amino groups.Back to article page