Figure 7

Patterns of nucleosomes near transcription factor binding sites (TFBSs). (A), patterns of nucleosomes near transcription factor binding sites (TFBS); (B) and (C), the relationship between nucleosome positioning and the distribution of TFBS, (B) for 13 independent MiRNA promoters [37], (C) for eight protein-coding genes' promoters (ZBED4, ZNF378, PIK4CA, EWSR1, SMC1L2, NF2, ARFGAP3, KIAA0542) [38]; the bold black lines represent the distribution of TFBS (the average binding score profile of 64 TFs, see methods), the area with shading are averaged curvature profile, in which reference lines are cut-off lines. The vertical blocks highlight the correspondences between NFR and the distribution of TFBS