Table 3 List of identified protein clusters with conserved β -signal.
From: Eukaryote-wide sequence analysis of mitochondrial β-barrel outer membrane proteins
Representative protein | Number of cluster member | Organism | Protein length | Conserved motif position | Subcellular Localization | Family and domain |
|---|---|---|---|---|---|---|
C-terminal β -signal | ||||||
SAM50-like protein CG7639 (Q9V784) | 12 | D. melanogaster | 443 | 435-442 | Mito OM (G) | SAM50/omp85 family (U), Bacterial surface antigen (I) |
SAM complex subunit of the mitochondrial outer membrane, putative (B9WEF8) | 6 | C. dubliniensis | 499 | 492-498 | OM (G) | Bacterial surface antigen (I) |
SAM50-like protein (A3LZ83) | 6 | P. stipitis | 489 | 473-480 | - | - |
SAM50 (P53969) | 5 | S. cerevisiae | 484 | 476-483 | Mito OM (U, G) | SAM50/omp85 family (U), Bacterial surface antigen (I) |
SAM50-like protein SpAC17C9.06 (Q10478) | 2 | S. pombe | 475 | 467-474 | Mito OM (G) | SAM50/omp85 family (U), Bacterial surface antigen (I) |
SAM50-like protein gop-3 (P46576) | 2 | C. elegans | 434 | 426-433 | Mito OM (G) | SAM50/omp85 family (U), Bacterial surface antigen (I) |
KLLA0E02223p (Q6CPU1) | 2 | K. lactis | 480 | 472-479 | OM (G) | Bacterial surface antigen (I) |
Predicted cell surface protein homologous to bacterial outer membrane proteins (ISS) (Q017Y3) | 2 | O. tauri | 521 | 508-515 | OM (G) | Bacterial surface antigen (I) |
TOM40 (P23644) | 36 | S. cerevisiae | 387 | 352-359 | Mito OM (U, G) | Tom40 family (U), Porin, eukaryotic type (I), Mitochondrial outer membrane translocase complex, subunit Tom40 (I) |
GA18230 (Q293I2) | 8 | D. pseudoobscura | 321 | 290-297 | Mito OM (G) | Porin, eukaryotic type (I) |
Outer mitochondrial membrane protein porin (B8NA08) | 5 | A. flavus | 346 | 337-344 | Mito OM (G) | Porin, eukaryotic type (I) |
Voltage-dependent anion-selective channel protein (A8I528) | 2 | C.reinhardtii | 276 | 268-275 | OM (G) | Porin, eukaryotic type (I) |
Predicted protein (B8BQH4) | 2 | T. pseudonana | 268 | 261-268 | OM (G) | Porin, eukaryotic type (I) |
cDNA FLJ52528, highly similar to Protein TOMM40-like (B7Z4T8) | 2 | H. sapiens | 210 | 202-209 | OM (G) | Porin, eukaryotic type (I) |
Mdm10 (P18409) | 5 | S. cerevisiae | 493 | 484-491 | Mito OM (U, G) | MDM10 family., Protein of unknown function DUF3722 (I) |
Mdm10 (A5DUG6) | 5 | L. elongisporus | 523 | 496-503 | Mito OM (U, G) | MDM10 family., Protein of unknown function DUF3722 (I) |
Internalβ-signal | ||||||
Probable mitochondrial import receptor sub-unit tom40 homolog (Q7RE39) | 10 | P. yoelii | 396 | 331-338 | Mito OM (U, G) | Porin, eukaryotic type (I) |
Putative uncharacterized protein (Q4CQ17) | 5 | T. cruzi | 479 | 417-424 | OM (G) | Bacterial surface antigen (I) |