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Table 2 Genes that displayed increased mRNA during lactation in all tissues

From: Differential gene expression in liver and small intestine from lactating rats compared to age-matched virgin controls detects increased mRNA of cholesterol biosynthetic genes

Transcript

Cluster ID

Gene Name

RL

RD

RJ

RIL

7027017

Acetyl-Coenzyme A acetyltransferase

1.98

(p = 0.0173)

2.40

(p = 0.0049)

1.80

(p = 0.0363)

2.19

(p = 0.0128)

7080099

Transmembrane protein 96

1.92

(p = 0.0001)

2.03

(p = 2.8e-05)

1.82

(p = 0.0002)

2.15

(p = 8.7e-06)

7113785

Hydroxysteroid(17-beta) dehydrogenase 7

1.71

(p = 2.1e-06)

1.54

(p = 4.7e-05)

1.19

(p = 0.045)

1.51

(p = 0.0001)

7132836

PDZ binding kinase predicted*

1.56

(p = 0.0222)

1.88

(p = 0.0031)

1.66

(p = 0.0054)

1.54

(p = 0.0227)

7139070

Farnesyl diphosphate farnesyl transferase

1.38

(p = 0.0009)

1.98

(p = 4.7e-08)

1.42

(p = 0.0004)

1.55

(p = 4.1e-05)

7144691

Sterol-C4-methyl oxidase-like

1.41

(p = 0.0015)

2.19

(p = 1.9e-07)

1.45

(p = 0.0008)

1.80

(p = 8.2e-06)

7166170

Isopentenyl-diphosphate delta isomerase

1.61

(p = 0.0006)

2.11

(p = 2.8e-06)

1.33

(p = 0.0226)

1.91

(p = 2.6e-05)

7169182

Kinesin family member 20a_predicted*

1.46

(p = 0.0012)

1.50

(p = 0.0010)

1.33

(p = 0.0104)

1.45

(p = 0.0013)

7186293

Mevalonate (diphospho) decarboxylate

2.65

(p = 3.8e-05)

2.15

(p = 0.0004)

1.49

(p = 0.0316)

1.73

(p = 0.0042)

7199743

RNA (guanine-9-) methyltransferase domain containing 2

1.18

(p = 0.009)

1.42

(p = 3.6e-06)

1.19

(p = 0.0066)

1.30

(p = 0.002)

7250653

CYP51

1.24

(p = 0.0116)

2.14

(p = 1.8e-09)

1.50

(p = 4.2e-05)

1.89

(p = 6.7e-08)

7280610

UDP-Galactose-4-epimerase

1.65

(p = 0.0006)

1.50

(p = 0.0042)

1.36

(p = 0.0243)

1.53

(p = 0.0023)

7291805

Dehydrodolichyl diphosphate synthase

1.37

(p = 0.0003)

1.36

(p = 0.0005)

1.27

(p = 0.0041)

1.17

(p = 0.0447)

7317317

Squalene epoxidase

1.83

(p = 2.4e-05)

2.27

(p = 5.6e-07)

1.72

(p = 0.0001)

1.70

(p = 0002)

7329323

Solute carrier 39 (zinc transporter) member 4

2.81

(p = 2.5e-10)

1.89

(p = 9.9e-08)

1.65

(p = 2.1e-06)

1.68

(p = 1.2e-06)

  1. To be considered part of a grouping, genes must have had a physiologic state p < 0.05 and at least one tissue simple effect p < 0.01. Reported p-values are the tissue simple effect p-values. The tissue simple effect p-value represents the comparison between Lactation and Control in the corresponding tissue. For the purposes of assigning patterns, the significance cutoff for the remaining tissues' simple effect p-values was set to p < 0.05. Abbreviations used as in Table 1. *Gene is at the Extended confidence level.
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BMC Genomics

ISSN: 1471-2164

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