From: Comparative analysis and assessment of M. tuberculosis H37Rv protein-protein interaction datasets
Source PPIs for homology transfer | STRING database experimental PPIs | ||
---|---|---|---|
Identify homology and transfer | PIDE >30 | HVAL >20 | Orthologues |
Coverage >0.2 | E-VALUE <1*e-6 | Identified by Inparanoid (default parameters) | |
E-VALUE< 1*e-10 | |||
Benchmark | M.tuberculosis H37Rv high-throughput B2H PPIs dataset | ||
Jaccard coefficient | 0.00354 | 0.00187 | 0.00289 |
Precision | 0.00375 | 0.00196 | 0.00339 |
Recall | 0.0588 | 0.0384 | 0.0190 |
Overlapping PPIs | 5 | 4 | 5 |
Benchmark | M. tuberculosis H37Rv predicted functional associations dataset from STRING database(with PPIs score above 770) | ||
Jaccard coefficient | 0.285 | 0.179 | 0.129 |
Precision | 0.355 | 0.236 | 0.239 |
Recall | 0.625 | 0.422 | 0.219 |
Overlapping PPIs | 656 | 830 | 525 |