Table 1 Representative P. falciparum proteins that are associated with PF10_0111, a putative 20S proteasome beta subunit with the highest connectivity. Protein-protein interactions revealed by yeast 2-hybrid assays are italicized.
From: Protease-associated cellular networks in malaria parasite Plasmodium falciparum
Functional description | Protein accession number | Annotation |
|---|---|---|
Nucleotide binding | PFL2345c | tat-binding protein homolog |
Cell cycle regulation | MAL13P1.337 | putative Skp1 family protein |
Transcriptional regulation | PF11_0293 | putative multiprotein bridging factor type 1 |
| Â | PF11_0477 | CCAAT-box DNA binding protein subunit B |
Translation | PF13_0346 | putative 60S ribosomal protein L40/UBI |
| Â | PF14_0141 | putative 60S ribosomal protein L10 |
| Â | PF11_0447 | putative translation initiation factor eIF-1A |
| Â | PFC0870w | putative elongation factor 1 (EF-1) |
| Â | PFE0350c | 60S ribosomal protein L4 |
| Â | PF14_0270 | putative apicoplast ribosomal protein L15 precursor |
| Â | PF11_0245 | putative translation elongation factor EF-1, subunit alpha |
Protein transport | PFL2060c | rab specific GDP dissociation inhibitor |
Protein modification | MAL7P1.19 | putative ubiquitin transferase |
Surface antigens | PF10_0345 | merozoite surface protein 3 |
| Â | PF10_0345 | merozoite surface protein 3 |
| Â | PF10_0348 | duffy binding-like merozoite surface protein |
| Â | PFE0060w | parasite-infected erythrocyte surface protein |
Unknown | MAL7P1.170 | Plasmodium exported protein, unknown function |