Figure 1

Features of the C. resistens DSM 45100 chromosome. (A), Circular representation of the annotated chromosome of C. resistens DSM 45100. The circles represent from the outside: circle 1, DNA base position [Mb]; circle 2, protein-coding regions transcribed clockwise; circle 3, protein-coding regions transcribed anticlockwise; circle 4, G + C content plotted using a 10-kb window; circle 5, G/C skew plotted using a 10-kb window. The plot was generated with the web version of the DNAPlotter tool. (B), Distribution of architecture imparting sequences in the C. resistens DSM 45100 chromosome. The distribution of the octamers G(A/T/C)GGGGGA and (T/C)GGGGGAG on the leading and lagging strands of the chromosome is shown. The origin of chromosomal replication (oriC) is marked. The deduced dif locus is located at around 1.23 Mbp of the chromosomal map. The sequence of the 28-bp dif site is shown. (C), Synteny plot between the chromosomes of C. resistens DSM 45100 and C. jeikeium K411. The X-Y plot shows dots forming syntenic regions between the two chromosomes. Each dot represents a C. resistens protein having an ortholog in the C. jeikeium genome, with co-ordinates corresponding to the position of the respective coding region in each genome. The orthologs were identified by reciprocal best BLASTP matches using the predicted amino acid sequences of C. resistens proteins. The detected genomic rearrangements are labeled; the positions of the prophages ΦCRES I and ΦCRES II in the chromosome of C. resistens DSM 45100 are marked.