Transcriptome analysis of the honey bee fungal pathogen, Ascosphaera apis: implications for host pathogenesis

BMC Genomics

Table 1 Pfam domains less abundant in Ascosphaera apis compared with related ascomycete species

Pfam domain	A. apis	A. capsulatus	A. otae	A. fumigatus	C. immitis	M. acridum	N. crassa
p450	11	29	82	77	40	87	42
Pkinase	54	146	176	113	138	147	109
Ankyrin	25	40	60	61	46	84	46
F-box	15	31	43	30	36	34	33
Fungal transcription factor	32	41	60	142	53	108	60
All zinc finger	210	324	292	439	329	331	304
All FAD binding	26	54	60	113	54	88	71
All NAD binding	20	28	50	82	36	66	41
All methyltransferase	37	52	93	94	59	88	79
All Rossman fold	234	283	379	609	338	520	406
Total domain types	2,627	2,720	2,917	3,103	2,833	3,029	3,038
Total domain matches	7,467	8,484	9,708	12,205	9,062	11,027	9,856
Undetected domains found in all other species	187	126	17	31	85	40	26
Total proteins searched	6,992	9,313	8,765	9,631	10,440	9,850	9,841

Domains were selected in which A. apis has at least six fewer proteins with a match (E < 0.1) than all other species examined. Only domains present in all seven ascomycete species were considered ( Ascosphaera apis, Ajellomyces capsulatus, Arthroderma otae, Aspergillus fumigatus, Coccidioides immitis, Metarhizium acridum, Neurospora crassa).

ISSN: 1471-2164