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Figure 5 | BMC Genomics

Figure 5

From: Time-course microarrays reveal early activation of the immune transcriptome and adipokine dysregulation leads to fibrosis in visceral adipose depots during diet-induced obesity

Figure 5

RT-qPCR validation. Time-dependent fold changes in (A) Lep mRNA, (B) Adipoq mRNA and (C) Retn mRNA expression based on HFD vs.ND group over 24 weeks. Microarray and RT-qPCR data shown as means ± S.D. *p < 0.05 based on wilcoxon t-test and student’s t-test, respectively. No statistical analysis, since we evaluated 1 pooled sample for microarray analysis in MAT. ND: normal diet (AIN-76), HFD: high-fat diet (20% fat, 1% cholesterol), EAT: epididymal adipose tissue, MAT: mesenteric adipose tissue, Lep: leptin, Adipoq: adiponectin, Retn: resistin.

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