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Figure 7 | BMC Genomics

Figure 7

From: Time-course microarrays reveal early activation of the immune transcriptome and adipokine dysregulation leads to fibrosis in visceral adipose depots during diet-induced obesity

Figure 7

Effect of high-fat feeding on transcription of key fibrotic genes in epididymal adipose tissue of C57BL/6 J mice over 24 weeks (HFD vs. ND group). (A) Extracellular matrix genes (TGF-β1, decorin, lumican and several MMPs), (B) adipose tissue-expressed collagen genes and (C) cathepsin genes in the adipose tissue measured by time-course microarrays. Fold changes in mRNA expression (HFD vs. ND) were displayed at each time-point over 24 weeks. Data shown as means ± S.D. *p < 0.05 based on wilcoxon t-test. ND: normal diet. HFD: high-fat diet.

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BMC Genomics

ISSN: 1471-2164

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