Comparative genomics of Brachyspira pilosicoli strains: genome rearrangements, reductions and correlation of genetic compliment with phenotypic diversity

Table 4 The number of genes with potential roles in pathogenesis and virulence in the three B. pilosicoli genomes

Role of putative gene	95/1000	B2904	WesB^a
Core genes involved in lipopolysaccharide biosynthesis^b	27	30	32
Chemotaxis
putative methyl-accepting chemotaxis protein	7	7	10
methyl-accepting chemotaxis protein A (mcpA)	2	0	2
methyl-accepting chemotaxis protein B (mcpB)	8	11	11
chemotaxis protein	15	15	15
Flagella	42	42	42
Adhesion and membrane protein
lipoprotein	21	31	29
variable surface protein	3	4	4
integral membrane protein	1	1	1
outer membrane protein	25	25	23
periplasmic protein	25	25	28
inner membrane protein	75	83	83
Host tissue degradation
haemolysis	12	12	12
phospholipase	2	3	2
peptidase	44	48	48
protease	19	19	17
Oxidative stress	7	7	7
Ankyrin-like protein	31	34	35
Phage and other mobile genetic elements	46	109	100
Total	412	506	501

The analysis categorised the genes from the genomes of B. pilosicoli 95/1000, B2904 and WesB.
^a The incomplete WesB strain genome was within one scaffold.
^b Core lipooligosaccharide (LOS) biosynthesis genes.

ISSN: 1471-2164