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Table 2 Top 10 co-expressed transcription factors with genes increased in expression with aging

From: GeneFriends: An online co-expression analysis tool to identify novel gene targets for aging and complex diseases

Transcription factor

p-value

Gene Name

C/ebpδ

7.90x10-34

CCAAT/enhancer binding protein (C/EBP), delta

C/ebpα

1.19x10-30

CCAAT/enhancer binding protein (C/EBP), alpha

C/ebpβ

3.78x10-30

CCAAT/enhancer binding protein (C/EBP), beta

Creg1

1.70x10-29

cellular repressor of E1A-stimulated genes 1

Nfe2l2

1.17x10-28

nuclear factor, erythroid derived 2, like 2

Irf7

8.04x10-26

interferon regulatory factor 7

Klf2

1.86x10-23

Kruppel-like factor 2 (lung)

Irf1

8.17x10-23

interferon regulatory factor 1

Ostf1

1.96x10-22

osteoclast stimulating factor 1

Atf3

2.09x10-22

activating transcription factor 3