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Table 3 Top 10 genes co-expressed with cancer-related genes

From: GeneFriends: An online co-expression analysis tool to identify novel gene targets for aging and complex diseases

Gene

Previous association evidence

Reference

Nfkbil2

Confers resistance to DNA damaging agents and is a component of the replication stress control pathway

[78]

Chtf18

Involved in checkpoint response and chromosome cohesion

[79]

Cdc25c

Over expression associated with poor prognosis of cancer

[40]

Cdc7

Effective in inhibition of cancer growth

[80]

E130303b06rik

No previous associations

 

Cep152

Involved in centriole duplication

[25]

Bc055324

No previous associations

 

Cenpp

Required for proper kinetochore function and mitotic progression

[81]

Anln

Increased in expression in lung carcinogenesis and suggested as target

[82]

Hirip3

No previous associations

 
  1. For a full list refer to Additional file 5.