Table 3 Summary of miR-107 correlation analyses for canonical and non-canonical miRNA-mRNA outcomes
From: Alternative mRNA fates identified in microRNA-associated transcriptome analysis
| Â | Accuracy | FPR | FNR |
|---|---|---|---|
miR Modulation | Â | Â | Â |
miR | R2: 1.000, p<0.0001 | R2: 1.000, p<0.0001 | R2: 0.997, p<0.0001 |
anti-miR | R2: 0.996, p<0.0001 | R2: 1.000, p<0.0001 | R2: 0.999, p<0.0001 |
Bidirectional | R2: 1.000, p<0.0001 | R2: 1.000, p<0.0001 | R2: 0.992, p<0.0001 |
Cell Type | Â | Â | Â |
HEK-293 | R2: 0.999, p<0.0001 | R2: 1.000, p<0.0001 | R2: 0.998, p<0.0001 |
HeLa | R2: 0.999, p<0.0001 | R2: 1.000, p<0.0001 | R2: 0.997, p<0.0001 |
Conservation | Â | Â | Â |
Conserved | R2: 0.990, p=0.0002 | R2: 0.675, p=0.1417 | R2: 0.519, p=0.2919 |
Non-Conserved | R2: 0.990, p=0.0001 | R2: 0.976, p=0.0008 | R2: 0.980, p=0.0006 |
Seed Sequence | Â | Â | Â |
8mer | R2: 0.993, p<0.0001 | R2: 0.875, p=0.0224 | R2: 0.955, p=0.0030 |
7mer-m8 | R2: 0.994, p<0.0001 | R2: 0.968, p=0.0016 | R2: 0.980, p=0.0006 |
7mer-1A | R2: 0.996, p<0.0001 | R2: 0.971, p=0.0012 | R2: 0.980, p=0.0006 |