Figure 3

Genomic alteration of triple-negative BCs and ER-negative BC cell lines. (A) Genomic profiles of 56 triple-negative BCs were obtained from Turner [31]. The proportion of samples for each group (triple-negative BCs, ”Cluster 2 and 3” BC cell lines) is plotted in which each genomic area is gained (green) or lost (red) according to their genomic position. (B) The frequency of triple-negative BCs in which the smoothed log2ratios of each BAC clone above 0.45 is plotted (y-axis) according to its genomic location (x-axis). (C) Using the same criteria for the aCGH data of BC cell lines, amplified BAC clones for each BC cell line (row) are represented as green lines along the genome. The separation between ”Cluster 2 and 3” BC cell lines are indicated with a red line.