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Table 1 Genes with ≥10-fold reduction in expression in DA.F344(Cia5a) compared with DA

From: The arthritis severity locus Cia5a regulates the expression of inflammatory mediators including Syk pathway genes and proteases in pristane-induced arthritis

Symbol

Name

Entrez Gene ID

Fold reduction

p-value

Tnn

Tenascin N

304913

71.69

8.6x10-13

Mmp9

Matrix metallopeptidase 9

81687

32.79

1.4x10-9

Cdc2

Cell division cycle 2, G1 to S and G2 to M

54237

24.16

1.6x10-5

Mmp3

Matrix metallopeptidase 3

171045

23.94

5.0x10-5

Ccnb2

Cyclin B2

363088

22.95

5.0x10-6

Cthrc1

Collagen triple helix repeat containing 1

282836

17.93

3.2x10-9

Col12a1

Collagen, type XII, alpha 1

25683

16.25

7.6x10-8

Slpi

Secretory leukocyte peptidase inhibitor

84386

16.16

6.4x10-4

Spc24

SPC24, NDC80 kinetochore complex component, homolog

363028

14.72

2.5x10-6

Emilin1

Elastin microfibril interfacer 1

298845

13.55

2.4x10-6

Prc1

Protein regulator of cytokinesis 1

308761

13.08

1.6x10-5

Emb

Embigin

114511

12.82

1.4x10-5

Nuf2

NUF2, NDC80 kinetochore complex component, homolog

304951

12.52

2.5x10-6

Lbp

Lipopolysaccharide binding protein

29469

11.82

8.0x10-5

Cks2

CDC28 protein kinase regulatory subunit 2

498709

11.62

5.9x10-6

Wisp1

WNT1 inducible signaling pathway protein 1

65154

11.59

9.0x10-8

Cxcl1

Chemokine (C-x-C motif) ligand 1

81503

10.88

4.3x10-4

Steap1

Six transmembrane epithelial antigen of the prostate 1

297738

10.61

1.7x10-4

LOC687334

Similar to cytoskeleton associated protein 2

687334

10.16

9.1x10-6