Table 1 Verified expressed gene fusions in the breast cancer cell line ZR-75-30 predicted from structural analysis
5’ gene | 3’ gene | Chromosomes involveda | Expression | In framee | Fusion (F) or Runthrough fusion (R) | |
|---|---|---|---|---|---|---|
5’ | 3’ | |||||
APPBP2 | PHF20L1 | 17 | 8 | yes | yes | F |
COL14A1 | SKAP1 | 8 | 17 | yes | yes | F |
TAOK1 | PCGF2 | 17 | 17 | yes b,d | yes | F |
USP32 | CCDC49 | 17 | 17 | yes d | no | F |
BCAS3 | HOXB9 | 17 | 17 | yes d | see text | F |
TRPS1 | LASP1 | 8 | 17 | yes | yes | R |
ERBB2 | BCAS3 | 17 | 17 | yes c | no | R |
DDX5 | DEPDC | 17 | 8 | yes c | yes | R |
PLEC1 | ENPP2 | 8 | 8 | yes c | yes | F |
TIAM1 | NRIP1 | 21 | 21 | yes b | yes | F |
ZMYM4 | OPRD1 | 1 | 1 | yes | no | F |
TIMM23 | ARHGAP32 | 10 | 11 | yes | no | R |
TMEM74 | APPBP2 | 8 | 17 | no | Â | F |
TRAPPC9 | STARD3 | 8 | 17 | no | Â | F |
SSH2 | PLXDC1 | 17 | 17 | no | Â | F |
TAOK1 | CA10 | 17 | 17 | no | Â | F |
HYLS1 | TIMM23 | 11 | 10 | no b | Â | F |
USP32 | RALYL | 17 | 8 | no | Â | F |
TMEM74 | ACACA | 8 | 17 | no | Â | F |
NUDCD1 | TAC4 | 8 | 17 | no | Â | R |
TRAPPC9 | HOXB6 | 8 | 17 | no | Â | R |
SSH2 | NFE2L1 | 17 | 17 | no | Â | R |
TTC35 | MKS1 | 8 | 17 | no | Â | R |
TMEM71 | CRYBA1 | 8 | 17 | no | Â | R |
CA3 | KIAA1429 | 8 | 8 | no | Â | R |
GRHL2 | NUDCD1 | 8 | 8 | no | Â | R |
SUPT6H | GPIHBP1 | 8 | 17 | no | Â | R |
PGAP3 | NOV | 8 | 17 | no | Â | R |
KIAA0100 | LY6H | 8 | 17 | no | Â | R |
TG | ERBB2 | 8 | 17 | no | Â | R |