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Table 4 Effect of a chronic Western diet on the expression of genes related to phospholipid metabolism (based on GO classification) in the small intestinea

From: C57Bl/6 N mice on a western diet display reduced intestinal and hepatic cholesterol levels despite a plasma hypercholesterolemia

Symbol

Gene name

FC

q-value

Cdipt

CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)

-1.29

0.015

Cds2

CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2

-1.29

0.020

Cept1

Choline/ethanolaminephosphotransferase 1

1.26

0.030

Chka

Choline kinase alpha

1.90

0.027

Lpcat3

Lysophosphatidylcholine acyltransferase 3

1.39

0.005

Lpgat1

Lysophosphatidylglycerol acyltransferase 1

1.52

< 0.001

Plscr2

Phospholipid scramblase 2

7.83

< 0.001

Plscr4

Phospholipid scramblase 4

24.31

< 0.001

Ppap2b

Phosphatidic acid phosphatase type 2B

2.51

0.022

  1. aAbbreviations: FC fold change (Western diet vs. control)