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Table 3 Mutation series examples

From: Automated extraction and semantic analysis of mutation impacts from the biomedical literature

notation

Mutation Series

:

The double mutant Thr48Ser: Trp93Ala and the triple mutant Thr48Ser:Trp57Met : Trp93Ala ...

/

For G223D, H225N, G223D/T224I, T224I/H225N, and E156/173D mutants, ...

-

Kinetic studies of the mutant A14S-Q15K-D36S- W37R indicated that the apparent Km . . .

double

a double mutant (N190V and W191S) and triple mutant (Q137M, L143F and H146L) resulted . . .

triple

the triple mutant, R501A,R451A,K439A, which eliminates all of . . .

quadruple

E130D/S325T/S477G/Q481K quadruple mutations in wild-type E. coli XL1-Blue.

quintuple

…The quintuple mutant V26T R47F A74G F87V L188K of P450BM-3(P450BM-3 QM) converts …

+

The reaction of the D179W+R258E+R272D variant of CiP with . . .