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Table 3 Prediction of the disease type by protein function

From: Predicting cancer-associated germline variations in proteins

GO sub-ontology

% var

Q

MCC

Sp(C)

Sn(C)

Sp(O)

Sn(O)

C

89

0.76

0.3

0.58

0.34

0.79

0.91

F

98

0.77

0.45

0.83

0.39

0.75

0.96

P

96

0.89

0.63

0.79

0.62

0.9

0.96

CFP

100

0.75

0.52

0.40

0.97

0.99

0.71

  1. GO sub ontology: C=cellular component, F=molecular function, P=biological process. % var= percentage of predicted variations. Predicted classes: C= Cancer; O= Other genetic diseases. For a definition of classes and scoring indexes see section: Measuring the performance.
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BMC Genomics

ISSN: 1471-2164

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