Figure 3

Domain peaks retaining mutations after the removal of mutations from gene peaks Depiction of the gene and domain landscape topographies corresponding to an instance where multiple genes contribute mutations to a shared domain, yet the removal of mutations from a significantly mutated gene peak leaves a significant number of mutations in the shared domain. Left side – top map shows the significant gene peak in the lower right corner of the map, bottom map shows the gene peak removed. Right side – top map shows the original domain peak, bottom map shows the domain peak with a significant number of mutations even after the removal of mutations from a significant gene peak.