Table 3 Performance for optimizing the combination of two drugs in the presence of noise.
|  | Noise level | Search type | Performance metric | Gur Game (simultaneous) | Gur Game (sequential) | Previous search algorithm[11](α= 1) | ARU algorithm (proposed) (α= 1) |
|---|---|---|---|---|---|---|---|
f2a(x) | (2%) | A | success rate unique comb. | 97% | 96% | 100% | 100% |
| Â | Â | Â | Â | 12.5 | 17.0 | 13.3 | 11.6 |
| Â | Â | B | success rate iterations | 97% | 95% | 100% | 100% |
| Â | Â | Â | Â | 37.8 | 45.2 | 25.8 | 20.0 |
| Â | (5%) | A | success rate unique comb. | 97% | 96% | 100% | 100% |
| Â | Â | Â | Â | 12.6 | 17.1 | 13.3 | 11.8 |
| Â | Â | B | success rate iterations | 97% | 95% | 100% | 100% |
| Â | Â | Â | Â | 38.0 | 45.4 | 26.6 | 20.2 |
| Â | (8%) | A | success rate unique comb. | 97% | 96% | 100% | 100% |
| Â | Â | Â | Â | 12.6 | 17.0 | 13.3 | 12.0 |
| Â | Â | B | success rate iterations | 97% | 95% | 100% | 100% |
| Â | Â | Â | Â | 38.2 | 45.4 | 26.8 | 20.4 |
f2b(x) | (2%) | A | success rate unique comb. | 10% | 10% | 99% | 99% |
| Â | Â | Â | Â | 3.9 | 4.2 | 57.0 | 45.1 |
| Â | Â | B | success rate iterations | 10% | 10% | 99% | 99% |
| Â | Â | Â | Â | 4.0 | 44 | 148.5 | 120.0 |
| Â | (5%) | A | success rate unique comb. | 9% | 9% | 98% | 98% |
| Â | Â | Â | Â | 4.1 | 4.5 | 62.9 | 52.2 |
| Â | Â | B | success rate iterations | 9% | 9% | 98% | 99% |
| Â | Â | Â | Â | 4.3 | 4.7 | 172.1 | 143.8 |
| Â | (8%) | A | success rate unique comb. | 8% | 9% | 97% | 98% |
| Â | Â | Â | Â | 4.1 | 4.7 | 66.2 | 55.6 |
| Â | Â | B | success rate iterations | 9% | 9% | 97% | 98% |
| Â | Â | Â | Â | 4.4 | 4.9 | 198.1 | 167.3 |
f2c(x) | (2%) | A | success rate unique comb. | 61% | 54% | 98% | 98% |
| Â | Â | Â | Â | 10.9 | 12.7 | 13.1 | 12.5 |
| Â | Â | B | success rate iterations | 60% | 54% | 98% | 98% |
| Â | Â | Â | Â | 33.1 | 36.0 | 35.9 | 35.2 |
| Â | (5%) | A | success rate unique comb. | 71% | 66% | 98% | 98% |
| Â | Â | Â | Â | 11.4 | 13.2 | 12.9 | 12.4 |
| Â | Â | B | success rate iterations | 60% | 54% | 98% | 98% |
| Â | Â | Â | Â | 33.2 | 35.4 | 36.7 | 36.0 |
| Â | (8%) | A | success rate unique comb. | 88% | 83% | 98% | 98% |
| Â | Â | Â | Â | 11.7 | 13.4 | 12.6 | 12.0 |
| Â | Â | B | success rate iterations | 6.% | 54% | 98% | 98% |
| Â | Â | Â | Â | 33.4% | 34.3 | 37.4 | 37.0 |
f2d(x) | (2%) | A | success rate unique comb. | 100% | 100% | 100% | 100% |
| Â | Â | Â | Â | 4.9 | 6.0 | 4.6 | 4.1 |
| Â | Â | B | success rate iterations | 96% | 9.% | 100% | 100% |
| Â | Â | Â | Â | 18.3 | 19.7 | 8.2 | 7.7 |
| Â | (5%) | A | success rate unique comb. | 100% | 100% | 100% | 100% |
| Â | Â | Â | Â | 4.9 | 5.7 | 4.3 | 4.1 |
| Â | Â | B | success rate iterations | 96.% | 91% | 100% | 100% |
| Â | Â | Â | Â | 18.4 | 19.6 | 8.1 | 7.5 |
| Â | (8%) | A | success rate unique comb. | 100% | 100% | 100% | 100% |
| Â | Â | Â | Â | 4.8 | 5.6 | 4.4 | 4.2 |
| Â | Â | B | success rate iterations | 96% | 91% | 100% | 100% |
| Â | Â | Â | Â | 18.6 | 19.6 | 8.1 | 7.1 |