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Table 2 The ρdiff scores of the 1st and 1000th ranked SNP pairs and their associated P-values

From: iLOCi: a SNP interaction prioritization technique for detecting epistasis in genome-wide association studies

Complete set of SNPs (355882 SNPs)

Disease

1stρdiff

1stP -value

1000thρdiff

1000thP -value

Avg. ρdiff± SD

BD

0.2878

1.1410e-7

0.2680

3.4206e-7

0.2718± 0.0035

CAD

0.9317

<2.2204e-16

0.9132

<2.2204e-16

0.9171± 0.0031

CD

0.3085

3.6109e-8

0.2849

1.3351e-7

0.2887± 0.0034

HT

0.2834

1.4510e-7

0.2626

4.6022e-7

0.2667± 0.0037

RA

0.9042

<2.2204e-16

0.8866

<2.2204e-16

0.8903± 0.0031

T1D

1.0731

<2.2204e-16

0.9996

<2.2204e-16

1.0040± 0.0056

T2D

0.3338

8.8226e-9

0.2159

6.1867e-6

0.2198± 0.0052

Gene-only SNPs (176148 SNPs)

Disease

1 st ρ diff

1 st P -value

1000 th ρ diff

1000 th P -value

Avg. ρ diff ± SD

BD

0.2447

1.2445e-6

0.2224

4.2957e-6

0.2259± 0.0032

CAD

0.9294

<2.2204e-16

0.9102

<2.2204e-16

0.9143± 0.0035

CD

0.2653

3.9790e-7

0.2248

3.7769e-6

0.2280± 0.0033

HT

0.1793

4.7229e-5

0.1561

1.7142e-4

0.1605±0.0043

RA

0.9040

<2.2204e-16

0.8832

<2.2204e-16

0.8875± 0.0036

T1D

1.0731

<2.2204e-16

0.9957

<2.2204e-16

1.0007± 0.0061

T2D

0.3338

8.8226e-9

0.2127

7.3731e-6

0.2168± 0.0052

  1. The highest and the lowest ρdiff scores including their associated P-values are displayed with the average scores of top 1000 SNP pairs from the analyses of WTCCC.
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BMC Genomics

ISSN: 1471-2164

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