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Table 4 Improvement in GWAS-based association FDR as multi-species gene ranking score increases.

From: Multi-species data integration and gene ranking enrich significant results in an alcoholism genome-wide association study

FDR

q-value

Total SNPs passing QC

Scored

Score ≥1

Score ≥1.5

Score ≥2

Score = 2.5

All SNPs

547920

91774

18988

7948

2293

210

< 0.9

48016

6399

1863

399

866

178

< 0.8

643

469

415

163

199

108

< 0.7

6

8

164

5

117

72

< 0.6

0

5

0

0

42

53

< 0.5

0

5

0

0

39

0

< 0.4

0

5

0

0

27

0

< 0.3

0

0

0

0

0

0

< 0.2

0

0

0

0

0

0

< 0.1

0

0

0

0

0

0

< 0.05

0

0

0

0

0

0

Min q

0.605

0.369

0.667

0.636

0.357

0.526