Figure 4

CP genes represented in pattern-oriented heatmaps. Transcripts were clustered based on expression patterns (n = 9) and heatmaps were constructed using the R pheatmap package. Each column corresponds to the transformed FPKM value of transcripts in duplicate, and each row corresponds to a gene. None of the genotypes had transcripts clustered in p9. Additionally, p4 in TGFΒ3−/− and p5 in TGFΒ3+/− did not contain transcripts. Therefore, the total number of CP gene patterns/genotype groups is 22. The increasing intensity of red to yellow signifies a higher level of expression (FPKM) in the given sample of a specific transcript. The list of genes for each particular pattern and genotype are shown in Additional file 9.