Table 1 Human genes identified by GWAS
Region | Trait | Genes |
|---|---|---|
1p32.3 | LDL | TMEM61, BSND, PCSK9, USP24 |
1p31.3 | TG | ANGPTL3*, DOCK7, ATG4C** |
1p13.3 | LDL | KIAA1324, SARS, CELSR2**, PSRC1, MYBPHL, SORT1 |
1p12 | T2D | ADAM30, NOTCH2 |
1q42.13 | TG, HDL | GALNT2 |
2p24.1 | LDL | APOB |
2p23.3 | T2D | NRBP1**, KRTCAP3, IFT172, FNDC4, GCKR, C2orf16, ZNF512 |
2p21 | T2D | THADA**, PLEKHH2 |
2q24.3 | FG | NOSTRIN*, SPC25, G6PC2, ABCB11** |
3p25.2 | T2D | PPARG** |
3p14.1 | T2D | ADAMTS9* |
3q27.3 | T2D | IGF2BP2*, C3orf65 |
5q13.3 | LDL | HMGCR, COL4A3BP |
6p22.3 | T2D | CDKAL1 |
6p21.32 | LDL | HLA-DPA1, COL11A2, RXRB**, SLC39A7, HSD17B8, MIR219-1, RING1**, VPS52, RPS18 |
7p15.2 | T2D | JAZF1 |
7p13 | FG | AEBP1, MIR4649, POLD2, MYL7, GCK**, YKT6, CAMK2B |
7q11.23 | TG | BAZ1B, BCL7B, TBL2, MLXIPL**, VPS37D, DNAJC30*, WBSCR22, STX1A |
8p21.3 | TG, HDL | LPL** |
8q24.11 | T2D | SLC30A8* |
8q24.13 | TG | TRIB1* |
9p21.3 | T2D | MTAP, CDKN2A, CDKN2B |
9q31.1 | HDL | ABCA1 |
10p13 | T2D | NUDT5, CDC123, CAMK1D |
10q23.33 | T2D | IDE*, KIF11*, HHEX** |
10q25.2 | T2D | TCF7L2** |
11p15.1 | T2D | NUCB2*, NCR3LG1, KCNJ11**, ABCC8* |
11p11.2 | T2D | EXT2, ALX4 |
11q23.3 | TG | BUD13, ZNF259, APOA5, APOA4, APOC3, APOA1, SIK3 |
12q15 | T2D | TSPAN8, LGR5 |
12q23.3 | HDL | MYO1H, KCTD10*, UBE3B, MMAB, MVK** |
15q21.3 | HDL | LIPC** |
16q12.1 | T2D | RPGRIP1L, FTO |
16q12.2 | HDL | CETP, NLRC5, SLC12A3**, HERPUD1, MIR138-2 |
18q21.1 | HDL | LIPG**, ACAA2 |
19p13.2 | LDL | SMARCA4, LDLR, SPC24, KANK2 |
19p13.11 | TG, LDL | GATAD2A, TSSK6, NDUFA13**, YJEFN3, CILP2, PBX4, LPAR2, GMIP, ATP13A1** |
19q13.33 | LDL | BCL3, CBC, BCAM, PVRL2, TOMM40**, APOE, APOC1, APOC4, APOC2, CLPTM1, RELB** |