NCBI gene symbola | AMPH/EIH | Specific gene function | General function | Reference |
---|---|---|---|---|
A3galt2 | 2 | Â | T-cell function? | NCBI Entrez Gene |
Abca1 | 2.18 | ATP-binding cassette (ABC) transporters | Cholesterol transport | NCBI Entrez Gene |
Actn3 | 2.47 | Cross links actin containing filaments | Â | NCBI Entrez Gene |
Ada | 0.41 | Adenosine deaminase | Immune system – modulates lymphocyte activity? | NCBI Entrez Gene |
Adamts9 | 2.97 | Metalloproteinase inhibitor | Vascular Function - angiogenesis? | PMID: 19052845 |
Akr1b8 | 4.49 | Unknown | Carcinogen-dependent tumor-associated protein | NCBI Entrez Gene |
Asns | 2.22 | Asparagine synthesis | Cell growth and differentiation – blocks cell proliferation | NCBI Entrez Gene |
Bzw2 | 2.04 | Transcription factor? | Â | NCBI Entrez Gene |
Cd14 | 3.14 | Binds bacterial lipopolysaccharides | Cell surface protein that mediates monocyte responses to bacterial lipopolysaccharides | NCBI Entrez Gene |
Cd93 | 1.75 | Â | Immune system function? | NCBI Entrez Gene |
Cyp1b1 | 2.61 | Cytochrome P450 monooxygenases | Lipid metabolism -polycyclic aromatic hydrocarbon, steroid metabolism or phospholipids metabolism | NCBI Entrez Gene |
Egfr | 2.01 | Epidermal growth-factor receptor | Cell growth and differentiation | NCBI Entrez Gene |
Eif2b3 | 1.75 | Subunit of initiation factor eIF2B | Â | NCBI Entrez Gene |
Emp1 | 1.88 | Epithelial membrane protein 1 | Â | NCBI Entrez Gene |
Enpp3 | 3.10 | Hydrolysis of extracellular nucleotides | Unknown - Found in immature glia, gut and pancreas | NCBI Entrez Gene |
Fcgr3 | 1.86 | Receptor on Fc portion of IgG | Immune system function | NCBI Entrez Gene |
Fgl2 | 3.11 | Regulates thrombosis | Vascular endothelium regulation of thrombosis | PMID: 15100314 |
Fmo5 | 4.03 | N-oxidation of amino-trimethylamine | Fmo5 not well characterized | NCBI Entrez Gene |
Foxj1 | 0.41 | Unclear in mammals | Unknown – characterization incomplete | NCBI Entrez Gene |
Fst b | 6.64 | Can Inhibit vesicular release of FSH | Adipogenesis? Cancer? | NCBI Entrez Gene PMID19470636 |
Gda | 2.53 | Hydrolytic deamination of guanine | Cell signaling? – incomplete characterization | NCBI Entrez Gene |
Gja5 | 2.57 | Endothelial gap junction protein | Vascular function - structural integrity | NCBI Entrez Gene |
Gpr4 | 2.20 | GCP receptor for lysophosphatidylcholine | May mediate monocyte transmigration through endothelial | NCBI Entrez Gene, PMID17364894 |
Has1 b | 7.20 | Regulates the biosynthesis of hyaluronan | Immune System - inflammation related? | PMID: 17611197 |
Ilr2* | 5.48 | Interleukin 1 receptor family | Inhibits the activity of Il-1 | NCBI Entrez Gene |
Ilrn* | 3.35 | Binds to Interleukin 1 receptor | Inhibits the effects of IL-1 | NCBI Entrez Gene |
Itpkc | 2.21 | Phosphorylates inositol triphosphate | Â | NCBI Entrez Gene |
Lbp | 4.15 | Binds LPS and interacts with the CD14 receptor | Acute-phase immunologic response to gram-negative bacterial infections | NCBI Entrez Gene |
Lrrc4c | 0.38 | Lrrc4c (NGL1) is a specific binding partner for netrin G1 | Has been implicated in axonal guidance | NCBI Entrez Gene |
Llgl1 | 2.14 | Â | Non-muscle myosin II heavy chain and a kinase associated | NCBI Entrez Gene |
Mt1a b | 2.77 | Protects against oxidative stress | Cardiovascular function - protection from ROS in diabetes? | PMID: 18249147 PMID: 18349110 |
Mthfd1l | 1.94 | Synthesis of tetrahydrofolate in the mitochondrion | Â | NCBI Entrez Gene |
Ndrg1 | 2.21 | Cytoplasmic protein involved in stress | Involved in endothelial cell migration | PMID: 19760510 |
Nef3 | 0.45 | Medium neurofilament protein | Biomarker of neuronal damage | NCBI Entrez Gene |
Nnij1 | 1.67 | Â | Nerve injury associated protein | NCBI Entrez Gene |
Ogfrl1 | 1.93 | Opioid growth factor receptor-like 1 | Â | NCBI Entrez Gene |
Olfm3 | 0.42 | Â | Associated with lung cancer | NCBI Entrez Gene |
Pmp22 | 1.79 | Â | Component of myelin in the peripheral nervous system | NCBI Entrez Gene |
Pstpip1 | 1.76 | Â | Immune system-related | NCBI Entrez Gene |
Ptprj | 1.89 | Protein tyrosine phosphatase | Cell cycle and differentiation | NCBI Entrez Gene |
Ptges | 3.02 | Synthesized PGE2 | Vascular Function - vasodilatation | NCBI Entrez Gene |
Ramp3 | 2.97 | Calcitonin receptor modulating protein | Angiogenesis and vascular integrity | PMID: 18097473 |
Reg3a | 23.49 | Extracellular matrix repair? | Inflammation – expressed in pancreatitis and liver cancer damage - function unknown in MAV | NCBI Entrez Gene |
Reg3b | 27.01 | Extracellular matrix repair? | Inflammation – related to pancreatic damage - function unknown in MAV | PMID: 19077460 |
Reg3g | 8.29 | Extracellular matrix repair? | Inflammation – related to pancreatic damage and development - function unknown in MAV | NCBI Entrez Gene |
Rrp9 | 1.77 | Â | Processing of 18 s rRNA during ribosome synthesis | NCBI Entrez Gene |
Rsad2 | 2.27 | Â | Bone formation? | NCBI Entrez Gene |
Sct | 4.93 | Induces gastric relaxation | Endocrine hormone in pancreas and gut – function in MAV may be stimulate bicarbonate secretion | NCBI Entrez Gene |
Slc15a1 | 33.90 | Hydrogen peptide co-transporter | Inflammation? – transports polypeptides in intestine - function unknown in MAV | NCBI Entrez Gene PMID: 19462432 |
Slco4a1* | 1.85 | Organic anion transporter | Â | NCBI Entrez Gene |
Slpi* | 6.58 | Â | Protects epithelial tissues from serine proteases | NCBI Entrez Gene |
Timp1 | 2.60 | Metallopeptidase inhibitor | Multiple functions some vascular-related | NCBI Entrez Gene |
Tmem2 | 2.72 | Membrane spanning protein? | Unknown- characterization incomplete | NCBI Entrez Gene |
Tmem63c | 2.02 | Membrane spanning protein? | Unknown- characterization incomplete | NCBI Entrez Gene |
Wnt4 | 1.73 | Â | Cell signaling and development | NCBI Entrez Gene |