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Table 4 Candidate genes in the epistatic QTL regions and their involvement in growth-related pathways

From: Genetic dissection of growth traits in a Chinese indigenous × commercial broiler chicken cross

Trait

Gene

Chr

Position bp/(cM)1

Pathway2

BW6

UBE2A ubiquitin-conjugating enzyme E2A

4

16506437 – 16512992 (55–55.1)

UMP

MARCH7 membrane-associated ring finger (C3HC4) 7

7

36187561 – 36207776 (99.8)

UMP

GR 48

HERC4 hect domain and RLD 4

6

10024961 – 10054292 (36.7)

UMP

ZBTB1 zinc finger and BTB domain containing 1

5

52791938 – 52805593 (135.1)

UMP

MID1 midline 1

1

124042084-124134384 (296.9)

UMP

FCR 68

RNF144A ring finger protein 144A

3

94598486 – 94657682 (206.8)

UMP

NRAS neuroblastoma RAS viral (v-ras) oncogene homolog

26

3847830 – 3854232 (43.6)

ER

FCR 810

ITCH itchy E3 ubiquitin protein ligase homolog

20

1769346 – 1829955 (7.5–7.7)

UMP

TGFA Transforming growth factor alpha

22

3012283 – 3020403 (41.1)

ER

  1. 1 The physical locations of the genes based on the WASHUC 3.1 build, and the genetic locations of the scored SNP markers located within the gene. 2 UMP: Ubiquitin-mediated proteolysis; ER: ErbB signalling.