Figure 3From: Distinct angiogenesis roles and surface markers of early and late endothelial progenitor cells revealed by functional group analysesUnique biological functions of different EPCs. The 737 and 665 early (A) and late (B) EPC genes were subjected to a Gene Ontology (GO) database search. These categories were selected from the “Biological Process” organizing principle in the GO database (http://www.geneontology.org/). The number of genes, gene symbols, and p values for each category that are significantly enriched are listed (p < 0.05). Underlined: discussed in the text. (C) Culture supernatant of early EPCs increases angiogenesis ability of late EPCs in 3D-angiogenesis assays. (D) Paracine factors uniquely expressed in early EPCs. (E) Validation of array data by real-time RT-PCR (n = 3). *: P < 0.05 by analysis of variance (ANOVA).Back to article page