Figure 5

Correlation networks of miR-93/miR-15 and their high confidence target genes. We used 10 prediction tools to obtain, based on public data, candidate miRNA-mRNA target interactions and we identified high confidence targets by mRNA and miRNA expression. We calculated Pearson correlation coefficients between miRNAs and their targets. Results of the analysis are presented here for miR-93 (A), and miR-15 (B). The color and shape of nodes are based on different node attributes available for the analyzed dataset. The red triangles, purple circles and orange diamonds in the network are indicating miRNAs, target genes, and transcription factors, respectively. Edges represent correlation between miRNAs and mRNAs, the color of the edges designate the type of interaction. Red is for positive and green is for negative correlation.