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Figure 1 | BMC Genomics

Figure 1

From: Integrated “omics” profiling indicates that miRNAs are modulators of the ontogenetic venom composition shift in the Central American rattlesnake, Crotalus simus simus

Figure 1

Proteomic analysis of the ontogenetic changes in the venom composition of C. simus . Panels A-F display reverse-phase HPLC profiles changes of pooled venoms collected from specimens from age 8-weeks to adulthood (≥36 months). Chromatographic fraction numbers and their identities correspond to those previously identified by Calvete et al. [Figure 1 and Table of ref. [29]. BIP, bradykinin-inhibitory peptide; BPP, bradykinin-potentiating peptides; Disi, disintegrin; SerProt, serine proteinase; PLA2, phospholipase A2; LAO, L-amino acid oxidase; PI and PIII, snake venom metalloproteases (SVMP) of class PI and PIII, respectively; Peaks 29, 9, 10, and 11, crotoxin A-chain [UniProtKB accession code P08878]; peak 12, crotoxin B-chain-1 [P62022]; peak 12a, crotoxin B-chain-2 [P24027].

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BMC Genomics

ISSN: 1471-2164

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