Figure 6
From: Spir2; a novel QTL on chromosome 4 contributes to susceptibility to pneumococcal infection in mice
Infection phenotypes for BYJCBAN6-4 mice. Kaplan-Meier survival curves, showing the cumulative survival for BYJCBAN6-4 mice heterozygous, homozygous for CBA/CaH or homozygous for BALB/cByJ at SNP 4_80 (A). Statistical significance (compared to BYJCBAN6-4 mice homozygous for BALB/cByJ, pair-wise comparison with the Log Rank test) is indicated by p values on the graph. (B) Average numbers of S. pneumoniae (Log CFU/ml) in the blood at 24 hours post-infection for BYJCBAN6-4 mice grouped by their genotype at SNPs 4_38, 4_47, 4_80 or 4_103. Error bars represent the standard error of the mean. The numbers of mice in each group are shown in brackets. Statistical significance (compared to BALB/cByJ homozygosity, unpaired t-test) is indicated by p values on the graph.