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Table 3 Genes encoding molecules with predicted transmembrane domains and/or a signal peptide are significantly enriched among mab-5- regulated genes

From: Functional transcriptomic analysis of the role of MAB-5/Hox in Q neuroblast migration in Caenorhabditis elegans

 

Down in lof

Up in lof

Down in gof

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Total

Fraction in gene set1

24/37

5/9

100/128

52/82

181/256

Binomial p value2

p = 0.0368

p = 0.1702

p < 0.0001

p = 0.0129

p < 0.0001

  1. 1This set includes only protein-encoding genes and not small RNA genes. From gene annotation files from Wormbase, there were 9546 genes with tmhmm and/or SignalP annotation out of 19245 total.
  2. 2Binomial distribution test comparing fractions of transmembrane and secreted proteins in the gene sets compared to the total fraction in the genome.
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BMC Genomics

ISSN: 1471-2164

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