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Table 2 Results for S. cerevisiae

From: Interfacing cellular networks of S. cerevisiae and E. coli: Connecting dynamic and genetic information

A) S. cerevisiae Biological Process

 

Degree

Betweenness

Transitivity

Hubscore

Closeness

GRN/PPN

32/1265

0/1265

2/1265

0/1265

0/1265

TRN/PPN

0/1057

0/1057

0/1057

0/1057

0/1057

GRN/TRN

1/1044

0/1044

1/1044

0/1044

0/1044

B) S. cerevisiae Cellular Component

GRN/PPN

4/295

0/295

7/295

5/295

0/295

TRN/PPN

0/245

0/245

0/245

0/245

0/245

GRN/TRN

0/241

0/241

0/241

0/241

0/241

C) S. cerevisiae Molecular Function

GRN/PPN

0/375

0/375

5/375

3/375

0/375

TRN/PPN

2/308

0/308

0/308

0/308

0/308

GRN/TRN

0/304

0/304

0/304

0/304

0/304

D) S. cerevisiae transitivity centrality GRN/PPN (Cellular Component)

GO

Term

Size

ρ

p f d r

 

GO:0031597

Cytosolic proteasome complex

202

0.30

0.002024

 

GO:0005875

Microtubule associated complex

560

0.16

0.009816

 

GO:0019005

SCF ubiquitin ligase complex

26

0.65

0.01706

 

GO:0031903

Microbody membrane

17

0.74

0.02134

 

GO:0000785

Chromatin

522

0.15

0.02134

 

GO:0000313

Organellar ribosome

17

0.74

0.02134

 

GO:0005654

Nucleoplasm

12

0.81

0.03283

 
  1. Spearman’s rank correlation coefficient test for centrality measures between the GRN, TRN and PPN of Gene Ontology subnetworks for A Biological Process, B Cellular Component and C Molecular Function. A-C Tests are performed for degree, betweenness, transitivity (local clustering coefficient), hubscore and closeness centrality. Each column, shows the number of significant terms and the total number of terms tested. D shows 7 terms for cellular components with significant transitivity centrality between theS. cerevisiae GRNand PPN.