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Table 1 Gene ontology analysis of differentially expressed genes

From: Behavioral and neurogenomic transcriptome changes in wild-derived zebrafish with fluoxetine treatment

Gene ontology

FDR corrected p-value

Category

Term

ID

DEG (n=411)

Up-regulated (n= 167)

Down-regulated (n=244)

BP

lipid metabolic process

GO:0006629

1.62E-03

 

6.01E-07

BP

lipid biosynthetic process

GO:0008610

8.22E-03

 

5.75E-05

BP

fatty acid metabolic process

GO:0006631

8.77E-03

 

2.21E-04

BP

very long-chain fatty acid metabolic process

GO:0000038

7.78E-03

 

1.99E-03

BP

fatty acid biosynthetic process

GO:0006633

1.09E-02

 

4.35E-04

BP

very long-chain fatty acid biosynthetic process

GO:0042761

7.78E-03

 

1.99E-03

BP

small molecule metabolic process

GO:0044281

1.06E-02

  

BP

organic acid metabolic process

GO:0006082

1.56E-04

1.83E-02

 

BP

oxoacid metabolic process

GO:0043436

1.56E-04

1.83E-02

 

BP

carboxylic acid metabolic process

GO:0019752

5.22E-04

1.43E-02

 

BP

single-organism biosynthetic process

GO:0044711

2.24E-03

  

BP

small molecule biosynthetic process

GO:0044283

1.93E-03

  

BP

organic acid biosynthetic process

GO:0016053

2.86E-04

  

BP

carboxylic acid biosynthetic process

GO:0046394

2.86E-04

  

BP

L-serine metabolic process

GO:0006563

2.66E-02

2.66E-03

 

BP

organonitrogen compound metabolic process

GO:1901564

 

4.70E-02

 

BP

organonitrogen compound biosynthetic process

GO:1901566

 

1.88E-02

 

BP

cellular amino acid metabolic process

GO:0006520

 

2.27E-03

 

BP

cellular amino acid biosynthetic process

GO:0008652

 

2.54E-02

 

BP

alpha-amino acid biosynthetic process

GO:1901607

 

1.66E-02

 

BP

serine family amino acid biosynthetic process

GO:0009070

 

6.35E-03

 

BP

response to virus

GO:0009615

 

3.05E-03

 

BP

monocarboxylic acid metabolic process

GO:0032787

  

2.07E-03

BP

monocarboxylic acid biosynthetic process

GO:0072330

  

2.60E-03

BP

steroid metabolic process

GO:0008202

  

4.99E-02

BP

cellular lipid metabolic process

GO:0044255

  

4.82E-03

BP

sterol metabolic process

GO:0016125

  

1.21E-02

MF

phosphorylase activity

GO:0004645

4.24E-02

 

7.31E-03

MF

glycogen phosphorylase activity

GO:0008184

1.72E-02

 

2.95E-03

MF

cofactor binding

GO:0048037

3.24E-02

  

MF

catalytic activity

GO:0003824

3.19E-02

  

MF

oxidoreductase activity

GO:0016491

2.96E-03

 

1.43E-03

MF

oxidoreductase activity, acting on CH-OH group of donors

GO:0016614

  

8.66E-03

MF

transferase activity, transferring acyl groups

GO:0016746

  

9.02E-03

MF

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen

GO:0016709

  

2.47E-02

  1. BP Biological Process, MF Molecular Function, DEG all differentially expressed genes. Blank cells indicate p > 0.05.
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BMC Genomics

ISSN: 1471-2164

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